health $wellness blog

An international placebo-controlled study led by Cedars-Sinai suggests that a targeted drug therapy that was developed by researchers at Cedars-Sinai is safe and effective at helping people with moderate to severe ulcerative colitis reach clinical remission. Results from the multicenter Phase II study, ARTEMIS-UC, were published in The New England Journal of Medicine. Ulcerative colitis is a type of inflammatory bowel disease (IBD) that damages the digestive tract, causing stomach cramping, diarrhea, weight loss and rectal bleeding. It affects as many as 900,000 people in the U.S., and current treatments are often only minimally effective. “Findings from this study are poised to have a remarkable impact on treatment for ulcerative colitis and IBD overall,” said study senior author and IBD research pioneer Stephan Targan, MD, the Feintech Family Chair in Inflammatory Bowel Disease and executive director of the F. Widjaja Inflammatory Bowel Disease Institute at Cedars-Sinai. “The inv...

New Delhi: Reviewing the bioequivalence (BE) study report of the fixed-dose combination (FDC) antidiabetic drug Dapagliflozin Propanediol Monohydrate plus Gliclazide plus Metformin Hydrochloride film-coated bilayer tablet, the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has granted approval to Eris Lifesciences to manufacture and market the proposed antidiabetic drug. However, this approval is subject to the condition of conducting the Phase IV clinical trial of the proposed FDC. This nod came after the firm presented a BE study report of Dapagliflozin Propanediol Monohydrate eq. to Dapagliflozin 10mg/10mg + Gliclazide IP (SR) 30mg/60mg + Metformin Hydrochloride IP (SR) 500mg/500mg film-coated bilayered tablet before the committee. Dapagliflozin is a sodium-glucose cotransporter 2 inhibitor used in the management of type 2 diabetes mellitus. Dapagliflozin is indicated as an adjunct treatment, alongside diet and exercise, ...

New Delhi- Through a recent notice, the Indian Council of Medical Research (ICMR), New Delhi has called for Research Proposals for only North Eastern Region Fellowships/Grants for the Year 2024-2025 under the ''Human Resource Development (IHRD) Scheme for Health Research" of the Department of Health Research (MoHFW) in the emerging fields of Medical/Clinical/Health Sciences. The Human Resource Development Scheme aims to provide opportunities for advanced training 111 biomedical and health research for creating a pool of trained & experienced human resources in India. Also Read:ICMR Calls For Research Proposals for 2024-2025, All Details Here The following Component of the Scheme Online research proposals are invited for the year 2024-2: from eligible applicants from North Eastern States (Arunachal Pradesh, Assam, Mampt:1 - , Meghalaya, Mizoram, Nagaland, Sikkim, Tripura): Short-term Fellowship at Indian Institute (1-3 months) Long Term Fellow...

Chandigarh: The 130th standing Finance Committee (SFC) meeting of the Postgraduate Institute of Medical Education and Research (PGIMER) Chandigarh has been rescheduled to October 6, 2024, due to Health Minister JP Nadda’s attendance at the nursing institute NINE’s convocation. The specific time and venue for the meeting have yet to be finalized.  The upcoming SFC is scheduled to address important issues, including manpower allocation for doctors’ security. This issue has gained urgency in light of recent assaults on healthcare professionals, highlighting the need for enhanced protective measures. It’s worth noting that the 129th SFC meeting was delayed and only took place after being postponed five times. Also Read:Kolkata doctor death case: AIIMS Doctors demand Central Protection Act, Strike continues The State Finance Commission (SFC) meeting is poised to focus on the urgent need for additional workforce resources to enhance security and safety on campus. This initiative re...

Chandigarh:  While considering the pleas filed by several hospitals in Punjab seeking the release of pending dues from the State Government under the Ayushman Bharat Scheme, the Punjab and Haryana High Court till October 16, attached the salaries of senior officials, including the Principal Secretary of the Health Department of the State, for failing to release the pending dues. "Let an affidavit be filed by the State Government of Punjab giving the details of the payments that have been made against bills since 30.12.2021 to 24.09.2024 alongwith the date on which such payment was released, within a period of two weeks from today. The salaries of Kumar Rahul, IAS, Principal Secretary, Department of Health, Ms. Babita, Chief Executive Officer, Mr. Deepak, Director and Ms. Sharanjit Kaur, Deputy Director, State Health Agency, Department of Health and Family Welfare, Punjab shall remain attached till the next date of hearing," ordered the HC bench. "This Court also tent...

New Delhi: The Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has granted permission to Pure and Cure Healthcare to conduct the bio-equivalence study of Ferric Maltol Capsules 30 mg as per the protocol presented. This came after the firm presented the proposal for grant of permission to manufacture and market of Ferric Maltol Capsules 30 mg along with bioequivalence study protocol (No. VRL-23-004, Ver-1.0, dated: 01.09.2023 and Phase III clinical trial waiver justification before the committee. Ferric maltol is a complex iron supplement used to treat iron deficiency in adults. Ferric maltol dissociates as the iron atom is donated to unknown iron uptake mechanisms, possibly beta 3 integrin or divalent metal transporter 1, in the ileum and duodenum. Once the iron is in circulation, it is associated with transferrin and ferritin. At the recent SEC meeting for Hematology held on September 10, 2024, the expert panel reviewed the...

Retinopathy associated with the use of hair dye aromatic amines (RAHDAA) is a rare form of retinopathy that is caused due to the use of hair dye. Recently researchers identified this in three individuals. The case findings were published in the journal JAMA Ophthalmology. A rare form of retinopathy, associated with the use of hair dyes containing aromatic amines (RAHDAA), has recently been reported in three middle-aged women that presented with multiple bilateral serous retinal detachments (SRDs), resembling MEK inhibitor-associated retinopathy, and appears to be linked to the disruption of the mitogen-activated protein kinase (MAPK) pathway. Discontinuation of the hair dye led to resolution of retinopathy within months.  Also Read:  Bilirubinemia May Protect Against Severe Retinopathy of Prematurity in Extremely Preterm Infants: Study One case was a 61-year-old woman without any significant medical history, developed bilateral blurry vision shortly after using a hair dye...